Abstract: According to the hydrogeological parameters affected to the prediction reliability of the mine water quantity, the related factor analysis method to predict many years water inflow quantity was provided for predicting.Based on Datang Tashan Mine of Datong Coal Mine as a case, a water flling geological model of Tashan Mine was established.The SPSS software was applied to analyze the relativity between the Tashan mine water inflow quantity and the mine accumulated coal productio n, the accumulated heading advance rate and the accumulated goaf area.Multi regression equation of the mine water inflow quantity was set up and a reliable predictio n of the mine water inflow could be realized.The results showed that the mine water inflow quantity of Tashan Mine was closely related to the accumulated coal producti on.When the coal mining was in No.3-5 seam of the mine, the mine water inflow quantity would be 4 972 m3/d.The study could provide reliable technical support to the mine water prevention and control in the mine.